Chromosome Studio was founded by siblings Davide and Sara Comelli. After completing their studies in graphic design—Davide at ISIA in Urbino and Sara at Le Gobelins in Paris—they established Chromosome Studio several years ago. The studio focuses primarily on graphic design projects, mural paintings (including large-scale murals), and illustrations.

Over the years, they have completed significant projects for international agencies, architectural firms, public and private entities, brands, and events in cities like Paris, Barcelona, Berlin, Sydney, and across Italy. They have also lived in three of these cities: Paris, Barcelona, and Berlin.

Their expertise combines a passion for pictorial research with their formal training in graphic design. They find it particularly intriguing to work on projects that consider and engage with the architectural space they occupy. Their extensive experience in mural art has led them to view architectural volumes as a communicative vehicle and a source of inspiration. This perspective has sparked various collaborations with architecture and design studios.

These interests have materialized in diverse projects for cultural and commercial venues, restaurants, hotels, trade show installations, scenography, signage, and urban revitalization interventions worldwide.

In addition to this synergy between painting and graphic design, they have also developed traditional graphic and illustrative projects, including visual identities, logos, and various communication supports and coordinated images.